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Updated: Sep 16, 2025

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
[Magnetic resonance imaging of the pediatric chest]
Daniel Gräfe1, Franz Wolfgang Hirsch2
1Institut für Kinderradiologie, Universitätsklinikum Leipzig, Liebigstraße 20A, 04103, Leipzig, Deutschland. daniel.graefe@medizin.uni-leipzig.de.
Background:
Magnetic resonance imagining (MRI) has become a well-established radiation-free alternative to computed tomography (CT) in pediatric imaging but is still rarely used for lung evaluation due to technical limitations such as low proton density and motion artifacts.
Objective:
To demonstrate how pediatric lung MRI can be performed reliably despite its known limitations and how recent technical innovations enhance its diagnostic potential.
Materials And Methods:
Based on clinical experience from a university pediatric radiology center, a standardized thoracic MRI protocol for children is presented. It includes respiratory-triggered T2-weighted sequences and, when available, ultra-short TE (UTE) sequences. Emerging techniques such as ventilation-perfusion MRI and real-time MRI are also discussed.
Results:
Most clinical questions can be addressed using respiratory-triggered T2-weighted sequences. UTE sequences improve visualization of aerated lung parenchyma and low-proton lesions. Real-time MRI significantly reduces motion artifacts and enables functional assessment, especially in unsedated infants and toddlers. Total exam time is 15-20 min.
Conclusion:
Pediatric lung MRI is a reliable, radiation-free alternative to CT in many cases. New sequence techniques like UTE and real-time MRI considerably expand its diagnostic range. Wider adoption could meaningfully reduce radiation exposure in children with chronic lung disease.
Insights
Pediatric lung MRI offers a reliable, radiation-free alternative to CT scans. Advanced techniques like ultra-short TE and real-time MRI significantly improve diagnostic capabilities for children.
Area of Science:
- Radiology
- Pediatric Imaging
- Medical Technology
Context:
- Magnetic resonance imaging (MRI) is a radiation-free imaging modality.
- Computed tomography (CT) is widely used in pediatric imaging.
- MRI is underutilized for pediatric lung evaluation due to technical limitations like motion artifacts and low proton density.
Purpose:
- To demonstrate reliable pediatric lung MRI techniques.
- To highlight how technical innovations enhance diagnostic potential.
- To present a standardized thoracic MRI protocol for children.
Summary:
- Standardized pediatric thoracic MRI protocol includes respiratory-triggered T2-weighted and ultra-short TE (UTE) sequences.
- Emerging techniques like ventilation-perfusion and real-time MRI are discussed.
- Real-time MRI reduces motion artifacts, aiding functional assessment in infants and toddlers.
Impact:
- Pediatric lung MRI is a viable, radiation-free alternative to CT.
- New sequences (UTE, real-time MRI) expand diagnostic capabilities.
- Wider adoption can reduce radiation exposure in children with chronic lung disease.
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