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    Area of Science:

    • Biomechanics
    • Robotics
    • Neuroscience

    Background:

    • Human-in-the-loop (HIL) optimization is effective for assistive tasks but not yet for training.
    • Conventional HIL methods struggle to incorporate neuromotor learning during training.
    • Neuromotor learning is crucial for adapting movement patterns, such as gait mechanics.

    Purpose of the Study:

    • To implement and evaluate dynamic Bayesian optimization (DBO) for HIL training of gait propulsion mechanics.
    • To investigate the effect of DBO on increasing the trailing limb angle (TLA) during walking.
    • To compare DBO with conventional Bayesian optimization (BO) in a HIL training context.

    Main Methods:

    • A single-parameter HIL optimization experiment using DBO was conducted.
    • Five participants walked on an instrumented treadmill, receiving exoskeleton-applied hip torque pulses.
    • The target was to increase the trailing limb angle (TLA); results were compared to a BO control condition.

    Main Results:

    • Significant increases in TLA were observed post-training in the DBO group, but not the BO group.
    • No significant group-level increases in TLA were found during the training phase.
    • A weak but significant effect of applied torque on TLA change suggested limited modulation achievability.

    Conclusions:

    • DBO demonstrated potential for facilitating post-training neuromotor adaptations in TLA.
    • Current HIL optimization paradigms may not be sufficient for direct gait training of specific metrics like TLA.
    • Future research should explore multi-parameter optimization and alternative propulsion metrics for enhanced gait training.