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Related Experiment Video

Updated: Sep 16, 2025

Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
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Puffing topography: a tool to evaluate vaping behavior and exposure risks.

Shaligram Sharma1, Maureen Meister1, Xiaojia He1

  • 1Chemical Insights Research Institute, UL Research Institutes, Marietta, GA, USA.

Inhalation Toxicology
|July 11, 2025
PubMed
Summary
This summary is machine-generated.

Understanding puffing topography (PT) is key to assessing electronic nicotine delivery systems (ENDS) risks. Factors like age, nicotine strength, and lifestyle influence vaping behavior and exposure to harmful emissions.

Keywords:
ENDSVapingbehaviore-cigarettepuffing topography

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Area of Science:

  • Public Health
  • Toxicology
  • Behavioral Science

Background:

  • Electronic Nicotine Delivery Systems (ENDS) popularity is rising among youth and adults.
  • Vaping behavior, termed puffing topography (PT), involves puff duration, flow rate, and session length.
  • PT metrics are crucial for assessing exposure to nicotine, VOCs, and particulate matter.

Purpose of the Study:

  • To review critical aspects of puffing topography (PT).
  • To explore how factors like lifestyle, gender, e-liquid composition, and device parameters influence exposure risks.
  • To highlight the importance of standardizing PT for ENDS safety and public health.

Main Methods:

  • Literature review summarizing current evidence on puffing topography.
  • Analysis of factors influencing ENDS usage patterns and exposure.
  • Discussion on the role of PT in developing ENDS standards.

Main Results:

  • Puff volume and flow rate are key determinants of hazardous emission exposure.
  • Vaping behavior is influenced by age of initiation, nicotine strength, and circadian patterns.
  • Lifestyle, gender, e-liquid characteristics, and device design impact exposure risks.

Conclusions:

  • Standardizing puffing topography is essential for evaluating vaping behavior and toxicant exposure.
  • Standardized PT can aid in developing consensus standards for ENDS.
  • This approach is vital for protecting public health from ENDS-related risks.