Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

85
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
85
Prediction Intervals01:03

Prediction Intervals

2.3K
The interval estimate of any variable is known as the prediction interval. It helps decide if a point estimate is dependable.
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y. 
2.3K
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

381
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
381
Distributions to Estimate Population Parameter01:26

Distributions to Estimate Population Parameter

4.3K
The accurate values of population parameters such as population proportion, population mean, and population standard deviation (or variance) are usually unknown. These are fixed values that can only be estimated from the data collected from the samples. The estimates of each of these parameters are sample proportion, the sample mean, and sample standard deviation (or variance). To obtain the values of these sample statistics, data are required that have particular distribution and central...
4.3K
Parametric Survival Analysis: Weibull and Exponential Methods01:14

Parametric Survival Analysis: Weibull and Exponential Methods

592
Parametric survival analysis models survival data by assuming a specific probability distribution for the time until an event occurs. The Weibull and exponential distributions are two of the most commonly used methods in this context, due to their versatility and relatively straightforward application.
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
592
Random Error01:04

Random Error

1.5K
Random or indeterminate errors originate from various uncontrollable variables, such as variations in environmental conditions, instrument imperfections, or the inherent variability of the phenomena being measured. Usually, these errors cannot be predicted, estimated, or characterized because their direction and magnitude often vary in magnitude and direction even during consecutive measurements. As a result, they are difficult to eliminate. However, the aggregate effect of these errors can be...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using network screening methods to determine locations with specific safety issues: A design consistency case study.

Accident; analysis and prevention·2017
Same author

Causal inference framework for generalizable safety effect estimates.

Accident; analysis and prevention·2017
Same author

A method to account for and estimate underreporting in crash frequency research.

Accident; analysis and prevention·2016
Same author

Estimating the safety effects of lane widths on urban streets in Nebraska using the propensity scores-potential outcomes framework.

Accident; analysis and prevention·2015
Same author

Comparison of safety effect estimates obtained from empirical Bayes before-after study, propensity scores-potential outcomes framework, and regression model with cross-sectional data.

Accident; analysis and prevention·2014

Related Experiment Video

Updated: Sep 8, 2025

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
04:35

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Published on: July 3, 2020

3.4K

Out-of-sample prediction and interpretation for random parameter generalized linear models.

Jonathan S Wood1, Vikash Gayah2

  • 1Iowa State University, 813 Bissell Rd, Ames, 50014, IA, USA.

Accident; Analysis and Prevention
|July 11, 2025
PubMed
Summary

This study introduces an exact statistical method for making accurate out-of-sample predictions with generalized linear models (GLMs) that include random parameters (RPs). This approach improves upon existing methods by providing direct predictions and variance estimation for RPs.

Keywords:
Distribution theoryGeneralized linear mixed modelsOut-of-sample predictionRandom parameters

More Related Videos

An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

2.2K
Using Eye Movements Recorded in the Visual World Paradigm to Explore the Online Processing of Spoken Language
09:27

Using Eye Movements Recorded in the Visual World Paradigm to Explore the Online Processing of Spoken Language

Published on: October 13, 2018

10.1K

Related Experiment Videos

Last Updated: Sep 8, 2025

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach
04:35

Development of an Individual-Tree Basal Area Increment Model using a Linear Mixed-Effects Approach

Published on: July 3, 2020

3.4K
An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

2.2K
Using Eye Movements Recorded in the Visual World Paradigm to Explore the Online Processing of Spoken Language
09:27

Using Eye Movements Recorded in the Visual World Paradigm to Explore the Online Processing of Spoken Language

Published on: October 13, 2018

10.1K

Area of Science:

  • Statistics
  • Econometrics
  • Transportation Engineering

Background:

  • Generalized linear models (GLMs) with random parameters (RPs) enhance model fit and address unobserved heterogeneity.
  • Predicting outcomes for new observations using RP-GLMs is challenging, with existing methods often yielding biased or computationally intensive results.

Purpose of the Study:

  • To develop a statistically rigorous and computationally efficient method for out-of-sample predictions in RP-GLMs.
  • To provide accurate prediction variance estimation for out-of-sample observations.
  • To derive closed-form equations for elasticities and marginal effects of RPs.

Main Methods:

  • Leveraging fundamental statistical theory and properties of RP distributions (normal, lognormal, triangular, uniform, gamma) within a log-link GLM framework.
  • Developing an exact prediction method and closed-form equations for elasticities and marginal effects.
  • Testing the proposed method using crash frequency prediction models from the Highway Safety Information System (HSIS).

Main Results:

  • The proposed exact method yields more accurate out-of-sample predictions compared to simulation-based approximations.
  • The method provides direct and accurate estimation of prediction variance for out-of-sample observations.
  • The approach is computationally simple and suitable for practical applications.

Conclusions:

  • The developed exact method offers a superior alternative for out-of-sample predictions in RP-GLMs.
  • This methodology facilitates the broader application of RPs in statistical modeling and research.
  • The findings are particularly relevant for transportation safety analysis and other fields utilizing GLMs.