Low-dose intra-arterial streptokinase: benefit versus risk

Twenty-six unselected patients presenting with acute arterial ischaemia of a limb were treated with low-dose intra-arterial streptokinase under the joint care of a radiologist and a vascular surgeon. The results are reported and complications described. It is suggested that co-operative radiological and surgical management is essential and a shortened protocol for the safer administration of the drug is suggested.