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Acute Cardiogenic Shock Secondary to Left Main Occlusion in a Patient with Behçet Disease

Harveen K Sekhon1, Sohail Sareh1, David Kellner2

  • 1Department of Cardiology, University of California-Los Angeles, Los Angeles, California, USA.

JACC. Case Reports
|July 11, 2025
PubMed

Insights

Coronary artery vasculitis is a rare complication of Behçet disease (BD). This case report details successful treatment of ST-elevation myocardial infarction and cardiogenic shock in a BD patient using mechanical circulatory support.

Area of Science:

  • Cardiology
  • Rheumatology
  • Immunology

Background:

  • Behçet disease (BD) is a rare multisystemic vasculitis with a predilection for venous and arterial thrombosis.
  • Coronary artery involvement in BD is exceptionally uncommon, carrying a high mortality risk.

Observation:

  • A patient with known Behçet disease presented with ST-segment elevation myocardial infarction (STEMI) and cardiogenic shock.
  • The clinical presentation suggested acute coronary artery vasculitis as the underlying cause.

Findings:

  • The patient's STEMI and cardiogenic shock were attributed to suspected coronary vasculitis secondary to Behçet disease.
  • Successful management was achieved with the implementation of mechanical circulatory support.

Implications:

  • This case highlights the importance of considering coronary vasculitis in BD patients presenting with acute coronary syndromes.
  • Mechanical circulatory support can be a life-saving intervention in managing severe cardiac complications of Behçet disease.
  • Further research is warranted to elucidate the pathophysiology and optimize treatment strategies for cardiac involvement in BD.

Keywords:
acute cardiogenic shockacute coronary syndromeautoimmune diseasepercutaneous coronary intervention

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