Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ulcerative colitis with arthritis and vasculitis.

J C Speiser, T L Moore, J Zuckner

    Clinical Rheumatology
    |September 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Polarisation-sensitive optical coherence tomography measurement of retardance in fibrosis, a non-invasive biomarker in patients with systemic sclerosis.

    Scientific reports·2022
    Same author

    Age-related alterations to working memory and to pyramidal neurons in the prefrontal cortex of rhesus monkeys begin in early middle-age and are partially ameliorated by dietary curcumin.

    Neurobiology of aging·2021
    Same author

    Mesenchymal derived exosomes enhance recovery of motor function in a monkey model of cortical injury.

    Restorative neurology and neuroscience·2019
    Same author

    Pilot study of intense pulsed light for the treatment of systemic sclerosis-related telangiectases.

    The British journal of dermatology·2012
    Same author

    Immune complexes and late complement proteins trigger activation of Syk tyrosine kinase in human CD4(+) T cells.

    Clinical and experimental immunology·2012
    Same author

    An investigation into the blood-flow characteristics of telangiectatic skin lesions in systemic sclerosis using dual-wavelength laser Doppler imaging.

    Clinical and experimental dermatology·2009
    Same journal

    Monosodium urate crystals induce lytic macrophage death partially dependent on both pyroptosis and necroptosis.

    Clinical rheumatology·2026
    Same journal

    A kaleidoscopic autoimmune syndrome (COVAS) following COVID-19 exposure.

    Clinical rheumatology·2026
    Same journal

    Risk of arrhythmia following ankylosing spondylitis, 2012-2023: a nationwide cohort study.

    Clinical rheumatology·2026
    Same journal

    Polyarteritis nodosa and antiphospholipid syndrome: a systematic review of a rare and challenging overlap between vasculitis and thrombotic vasculopathy.

    Clinical rheumatology·2026
    Same journal

    Association of metformin with osteoarthritis progression and total joint arthroplasty: evidence from the UK Biobank, a large population-based cohort study.

    Clinical rheumatology·2026
    Same journal

    Six-session non-operative exercise program yields sustained benefits for up to 18 months in end-stage knee osteoarthritis: a retrospective cohort study.

    Clinical rheumatology·2026
    See all related articles

    This case study details a child with ulcerative colitis (UC) experiencing rare complications like arthritis, vasculitis, and coagulopathy. These unusual manifestations highlight the diverse and severe potential impacts of pediatric UC.

    Area of Science:

    • Pediatric Gastroenterology
    • Rheumatology
    • Immunology

    Background:

    • Ulcerative colitis (UC) is a chronic inflammatory bowel disease primarily affecting the colon.
    • While UC is diagnosed in children, its extraintestinal manifestations (EIMs) in this age group are less understood.
    • Understanding EIMs is crucial for comprehensive pediatric IBD management.

    Observation:

    • A pediatric patient with ulcerative colitis presented with numerous unusual complications.
    • Arthritis was noted, preceding the onset of colitis.
    • The patient also developed vasculitis, hepatitis, pleuritis, pericarditis, cryoglobulinemia, and disseminated intravascular coagulopathy (DIC).

    Findings:

    • The co-occurrence of arthritis, vasculitis, hepatitis, pleuritis, pericarditis, cryoglobulinemia, and DIC is exceptionally rare in pediatric ulcerative colitis.

    Related Experiment Videos

  • Arthritis preceding colitis onset suggests a complex interplay of autoimmune processes.
  • Literature review confirmed the infrequent occurrence of these specific EIMs in pediatric UC patients.

    • Implications:

    • This case underscores the potential for severe and varied EIMs in pediatric ulcerative colitis.
    • Highlights the need for vigilant monitoring for systemic complications in children with UC.
    • Suggests further research into the pathogenesis of EIMs in pediatric IBD is warranted.