Endophthalmitis caused by Abiotrophia defectiva with initial presentation as retinal vasculitis: a case report
Xiaojie Lu1, Bei Liu1, Tiemei Yie1
1Shaanxi Eye Hospital, Xi'an People's Hospital (Xi'an Fourth Hospital), Affiliated People's Hospital, Northwest University, Xi'an, 710004, Shaanxi, China.
Journal of Medical Case Reports
|July 11, 2025
Summary
This case report details a rare instance of endophthalmitis caused by Abiotrophia defectiva, initially presenting as retinal vasculitis. Prompt recognition and treatment of this unusual ocular infection are crucial for improving patient vision.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Abiotrophia defectiva is typically linked to endocarditis, not intraocular infections.
- Intraocular infections caused by Abiotrophia defectiva are exceptionally rare.
- This study highlights a unique presentation of endophthalmitis.
Purpose of the Study:
- To report a rare case of endophthalmitis caused by Abiotrophia defectiva.
- To describe the initial presentation of retinal vasculitis in this case.
- To emphasize the importance of identifying atypical pathogens in ocular infections.
Main Methods:
- A case presentation of a 50-year-old male with decreased vision.
- Clinical examination revealed signs of retinal vasculitis progressing to endophthalmitis.
- Diagnostic procedures included anterior chamber irrigation, vitreous tap, and vitrectomy with cultures.
- Treatment involved intravitreal injections and surgical intervention.
Main Results:
- Abiotrophia defectiva was identified as the causative agent through cultures.
- The patient initially presented with symptoms suggestive of retinal vasculitis.
- The condition rapidly progressed to endophthalmitis.
- Prompt and effective treatment led to improved visual acuity.
Conclusions:
- This case illustrates a rare instance of endophthalmitis due to Abiotrophia defectiva.
- The initial presentation mimicked retinal vasculitis.
- Early diagnosis and management of unusual pathogens are vital for favorable visual outcomes in postoperative ocular infections.
More Related Videos
Related Concept Videos
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Photoreceptors and Visual Pathways
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...


