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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
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The Impact of Cardiovascular Diseases on Postoperative Complications in Orthopedic Trauma Patients

Felix Erne1,2, Larissa Mühlberger1, Christoph Ihle1,3

  • 1Siegfried Weller Research Institute, BG Unfallklinik, Department of Trauma and Reconstructive Surgery, Eberhard Karls University Tuebingen, Schnarrenbergstr. 95, 72076 Tuebingen, Germany.

Diagnostics (Basel, Switzerland)
|July 12, 2025
PubMed

Insights

Cardiovascular diseases (CVD) significantly increase postoperative complications after trauma surgery, especially with lower leg fractures. Addressing CVD risk factors is crucial for improving patient outcomes.

Area of Science:

  • Orthopedic Surgery
  • Cardiology
  • Trauma Care

Background:

  • Cardiovascular diseases (CVD) are a major global health concern, impacting morbidity and mortality.
  • A healthy cardiovascular system is vital for physical stress adaptation.
  • This study investigates the link between CVD and postoperative complications in trauma patients.

Purpose of the Study:

  • To examine the relationship between cardiovascular diseases and postoperative complications following trauma surgery.
  • To identify specific CVDs and injury types associated with increased complication rates.
  • To determine factors influencing complication development in trauma patients with CVD.

Main Methods:

  • A cohort of 1262 patients was analyzed from a Level I trauma center in Germany.
  • Data included cardiovascular disease burden, injury characteristics, and severity.
  • Postoperative complications were recorded using the Clavien-Dindo classification.

Main Results:

  • Patients with lower leg fractures showed higher complication rates, particularly with heart valve diseases and chronic venous insufficiency.
  • Age and sex did not significantly impact complication rates.
  • Multivariate analysis revealed that the number of CVDs, nutritional status, smoking, and mobility were key factors influencing complications.

Conclusions:

  • Cardiovascular diseases significantly elevate complication rates after trauma surgery.
  • Trauma-related extremity conditions are more severe in patients with co-existing CVD.
  • Personalized treatment strategies incorporating cardiovascular risk factor management are essential for better outcomes.

Keywords:
Clavien–Dindo classificationcardiovascular diseasesfractures of the upper and lower extremitiesorthopedic trauma surgerypostoperative complications

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