Level of Healthcare Facility and Psychosocial Factors Influence Perceived Self-Efficacy for Appropriate Use of Hydroxyurea: Experience from Caregivers of Children with Sickle Cell Disease in Tanzania
View abstract on PubMed
Summary
This summary is machine-generated.Caregivers with high self-efficacy are more likely to administer hydroxyurea (HU) to children with sickle cell disease (SCD). Enhancing psychosocial support for caregivers can improve HU use in Tanzania.
Area Of Science
- Medical Sciences
- Public Health
- Psychology
Background
- Sickle cell disease (SCD) presents significant physical and psychosocial challenges.
- Hydroxyurea (HU) is effective in preventing SCD complications and improving quality of life.
- Underutilization of HU in Tanzania necessitates investigation into factors influencing its use.
Purpose Of The Study
- To investigate factors associated with caregivers' self-efficacy in using HU for children with SCD.
- To examine the relationship between caregivers' self-efficacy and HU usage in pediatric SCD patients.
Main Methods
- A cross-sectional study involving 374 caregivers of children with SCD in Dar-es-Salaam.
- Utilized validated scales for self-efficacy, social support, and depressive symptoms.
- Data collected from May to August 2023 at regional and national hospitals.
Main Results
- High perceived self-efficacy for medication use was observed in three-quarters of caregivers.
- Factors positively associated with self-efficacy included attending national hospitals, high social support, and absence of depressive symptoms.
- Caregivers with high self-efficacy were 5.3 times more likely to administer HU.
Conclusions
- Caregivers' self-efficacy for appropriate HU use is influenced by hospital level and psychosocial factors.
- Interventions targeting psychosocial support can enhance self-efficacy.
- Improving self-efficacy is recommended to increase HU utilization in children with SCD in Tanzania.
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