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Beyond the Incision: Pediatric Postoperative Sepsis Risk Patterns and Related Adverse Events in U.S. Inpatient Care.

Michael Samawi1, Gulzar H Shah1, Linda Kimsey1

  • 1Department of Health Policy and Community Health, Jiann-Ping Hsu College of Public Health, Georgia Southern University, P.O. Box 8015, Statesboro, GA 30460, USA.

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Summary
This summary is machine-generated.

Postoperative sepsis (POS) affects 12.65% of pediatric discharges, with major surgery and large urban teaching hospitals being key risk factors. Targeted infection control is crucial for reducing this pediatric safety event.

Keywords:
HCUP Kids’ Inpatient Database (KID)Pediatric Quality Indicators (PDIs)health disparitieshealthcare-associated infectionshospital characteristicspatient safetypediatric surgerypostoperative sepsisrisk factors

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Area of Science:

  • Pediatric Safety
  • Healthcare Quality Improvement
  • Infectious Disease Epidemiology

Background:

  • Postoperative sepsis (POS) is a critical pediatric safety concern.
  • It is tracked by the Agency for Healthcare Research and Quality's Pediatric Quality Indicator 10 (PDI 10).

Purpose of the Study:

  • To examine the incidence and predictors of POS in U.S. inpatient pediatric care.
  • To identify patient- and hospital-level factors associated with POS.

Main Methods:

  • Utilized the 2019 Kids' Inpatient Database (KID), a national sample of pediatric discharges.
  • Performed multivariable logistic regression analysis to identify risk factors.

Main Results:

  • POS was identified in 12.65% of approximately 5.24 million pediatric discharges.
  • Major surgery, large urban teaching hospitals, and surgical/injury-related admissions were significant risk factors.
  • Hospital region, ownership, bed size, and race/ethnicity showed varied associations with POS risk.

Conclusions:

  • Age and sex were not significant independent predictors of POS.
  • Findings highlight the need for targeted infection control in high-risk settings.
  • Supports quality improvement initiatives to decrease the burden of surgical sepsis in children.