Evidence-Based Weight Management for Fertility Preservation in Endometrial Cancer Patients: Developing a Complex...

Area of Science:

• Reproductive Endocrinology
• Gynecologic Oncology
• Behavioral Science

Background:

• Endometrial cancer (EC) patients undergoing fertility preservation require tailored weight management support.
• Existing interventions lack standardization for this specific patient population.
• Midwives play a crucial role in integrating reproductive and oncologic care.

Purpose of the Study:

• To develop a standardized, evidence-based weight management intervention program for EC patients pursuing fertility preservation.
• To establish a scientific foundation for midwives to implement this intervention.
• To enhance patient outcomes within the context of fertility preservation and cancer survivorship.

Main Methods:

• The intervention was developed following the Medical Research Council framework and WHO guideline development handbook.
• A four-stage process included establishing a group, theoretical basis, evidence synthesis, and program refinement.
• Delphi consultation with experts achieved a 100% response rate and high expert authority (0.83).

Main Results:

• The final program comprises 6 primary, 18 secondary, and 53 tertiary components.
• The Delphi process confirmed expert consensus on the intervention's components and structure.
• The intervention is designed for practical application by healthcare providers.

Conclusions:

• The developed weight management intervention is scientifically sound and clinically feasible.
• This program offers a structured approach for managing weight in EC patients undergoing fertility preservation.
• It empowers midwives to deliver integrated care in oncology and reproductive health settings.