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Updated: Sep 16, 2025

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Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability
Published on: July 25, 2025
574
Time Course of Functional Recovery Following Single-Level Anterior Lumbar Interbody Fusion with and Without Posterior
Tejas Subramanian1,2, Stephane Owusu-Sarpong1, Sophie Kush1,2
1Department of Spine Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY 10021, USA.
Journal of Clinical Medicine
|July 12, 2025
Summary
This study defines recovery timelines after anterior lumbar interbody fusion (ALIF), showing significant functional improvements within one year for patients undergoing stand-alone or instrumented procedures.
Area of Science:
- Spine surgery
- Orthopedics
- Neurosurgery
Background:
- Anterior lumbar interbody fusion (ALIF) is a common procedure for degenerative lumbar spine conditions.
- Postoperative recovery timelines for ALIF are not well-established, impacting patient expectations and care.
- Understanding recovery trends is crucial for optimizing patient outcomes.
Purpose of the Study:
- To define the temporal recovery trends after primary, single-level ALIF.
- To compare recovery between stand-alone (SA) and percutaneous posterior instrumentation (PI) techniques.
- To establish benchmarks for functional recovery and return to activity.
Main Methods:
- Retrospective single-institution study of 143 patients undergoing ALIF (90 SA, 53 PI).
- Assessment of patient-reported outcome measures (PROMs) including Oswestry Disability Index (ODI), Visual Analog Scale (VAS) for pain, and SF-12 Physical Component Score (PCS).
- Data collected preoperatively and at multiple time points up to 2 years postoperatively.
Main Results:
- Significant improvements in PROMs were observed through 1 year post-surgery.
- Back pain (VAS-back) improved by 2 weeks; disability (ODI) and physical function (SF-12 PCS) improved after 6 weeks.
- Over 50% achieved minimum clinically important difference (MCID) by 6 months, with continued gains through 1 year. Recovery was comparable between SA and PI groups.
Conclusions:
- This study provides time-specific recovery benchmarks for ALIF surgery.
- Findings can guide surgical decision-making and patient education regarding recovery expectations.
- Established benchmarks aid in optimizing postoperative care and managing patient expectations for functional milestones.

