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Updated: Sep 16, 2025

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Published on: May 28, 2014

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"Non-Classical" Platinum Complexes: A Concise Review.

Adriana Bakalova1, Nina Ruseva2, Emiliya Cherneva1,3

  • 1Department of Chemistry, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav Str., 1000 Sofia, Bulgaria.

International Journal of Molecular Sciences
|July 12, 2025
PubMed
Summary

New platinum complexes, including trans-configured and Pt(IV) types, show promise as less toxic anticancer drugs. These non-classic platinum compounds exhibit significant cytotoxic activity, challenging traditional treatment paradigms.

Keywords:
Pt(IV) complexescytotoxic activitymixed ammine/amine platinum complexestrans-Pt complexes

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