Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anatomy of the Intestines01:23

Anatomy of the Intestines

74.1K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
74.1K
Obesity01:24

Obesity

622
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
622
Regulation of Food Intake01:30

Regulation of Food Intake

484
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
484

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

All-Trans Retinoic Acid Attenuates Inflammation and Insulin Resistance Induced by Adipocyte-Macrophage Coculture.

Molecules (Basel, Switzerland)·2025
Same author

Secretory Production of Plant Heme-Containing Globins by Recombinant Yeast via Precision Fermentation.

Foods (Basel, Switzerland)·2025
Same author

Anti-Cancer Strategies Using Anaerobic Spore-Forming Bacteria <i>Clostridium</i>: Advances and Synergistic Approaches.

Life (Basel, Switzerland)·2025
Same author

A Comprehensive Review Exploring the Protective Role of Specific Commensal Gut Bacteria against <i>Salmonella</i>.

Pathogens (Basel, Switzerland)·2024
Same author

Yeast cell wall mannan structural features, biological activities, and production strategies.

Heliyon·2024
Same author

Reduction of Ethyl Carbamate in an Alcoholic Beverage by CRISPR/Cas9-Based Genome Editing of the Wild Yeast.

Foods (Basel, Switzerland)·2023

Related Experiment Video

Updated: Sep 16, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.7K

Using Gut Microbiota Modulation as a Precision Strategy Against Obesity.

Kwang-Rim Baek1, Saloni Singh1, Hye-Seon Hwang1

  • 1Department of Food Science and Biotechnology, Seoul National University of Science and Technology, Seoul 01811, Republic of Korea.

International Journal of Molecular Sciences
|July 12, 2025
PubMed
Summary

The gut microbiome significantly impacts obesity development. Modulating gut bacteria with probiotics and prebiotics offers a novel strategy for obesity prevention and treatment.

Keywords:
gut microbiotahost–microbe interactionmetabolic disordermicrobiome engineeringobesity

More Related Videos

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

29.5K
Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

4.4K

Related Experiment Videos

Last Updated: Sep 16, 2025

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
07:15

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota

Published on: July 31, 2019

9.7K
Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
11:22

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing

Published on: October 15, 2019

29.5K
Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

4.4K

Area of Science:

  • Microbiology
  • Metabolic Disorders
  • Human Health

Background:

  • Obesity is a global health crisis with complex origins.
  • Emerging research implicates the gut microbiota in metabolic regulation and obesity.
  • Understanding these microbial interactions is key to developing new therapies.

Purpose of the Study:

  • To review the intricate relationship between gut microbiota composition and obesity.
  • To elucidate the mechanisms by which microbial communities influence host metabolism and energy balance.
  • To explore microbiota-targeted interventions for obesity management.

Main Methods:

  • Comprehensive literature review of studies on gut microbiota and obesity.
  • Analysis of microbial taxa, their metabolites (e.g., short-chain fatty acids), and host signaling pathways.
  • Evaluation of precision strategies for gut microbiome modulation.

Main Results:

  • Alterations in gut microbiota composition are linked to obesity.
  • Microbial metabolites and their interactions with host pathways significantly affect energy homeostasis.
  • Specific microbial profiles are associated with metabolic dysfunction.

Conclusions:

  • The gut microbiome plays a critical role in the pathogenesis of obesity.
  • Targeted modulation of the gut microbiota, including probiotics and prebiotics, presents a promising therapeutic avenue.
  • Further research into microbiota engineering could lead to innovative obesity treatments.