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Polynucleotide Mixture Attenuates Ultraviolet B-Induced Skin Pigmentation.

Seyeon Oh1, Hee-Dae Jeon2, Nark-Kyoung Rho3

  • 1Functional Cellular Networks Laboratory, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21999, Republic of Korea.

International Journal of Molecular Sciences
|July 12, 2025
PubMed
Summary

Polynucleotide (PN) and a PN mixture (PNM) effectively reduce skin darkening by decreasing oxidative stress and inflammation. PNM demonstrated a stronger anti-melanogenic effect than PN alone in UVB-exposed skin.

Keywords:
NLRP3 inflammasomemelanogenesispolynucleotideskin pigmentation

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