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Clin-STAR Corner: Practice Changing Advances in Diabetes Care
Anna R Kahkoska1,2,3, Jacob Ortega4, Anika Bilal5
1Division of Endocrinology and Metabolism, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Background:
Diabetes is common among older adults. While most cases are type 2, treatment advances and more adult-onset cases have led to more individuals living with type 1 diabetes. All older adults with diabetes are at an increased risk for hypoglycemia, yet this risk is especially high among those with type 1 diabetes due to the lifelong requirement for insulin. Advanced diabetes technologies-such as continuous glucose monitoring (CGM) and automated insulin delivery systems (AID)-can improve glycemic management, enhance safety, and reduce complications in insulin-requiring individuals.
Aims:
We aimed to review randomized controlled trials that tested the feasibility and effectiveness of diabetes technology in older adult populations.
Methods:
We conducted a searchfrom 08/15/2024-09/15/2024 that was updated 01/15/2025. We selected six studies testing CGM and AID use in adults ≥ 60 with diabetes, ≥ 3 months follow-up, ≥ 30 participants, and primary glycemic outcomes, prioritizing methodological rigor and clinical relevance.
Results:
The selected studies demonstrated that CGM reduces hypoglycemia and increases time spent in the target glucose range (70-180 mg/dL) compared to blood glucose monitoring in older adults, with benefits seen across insulin regimens and diabetes types. AID systems reduce both hypoglycemia and hyperglycemia in older adults with type 1 diabetes. Participant adherence and acceptability measures were consistantly high.
Discussion:
These trials suggest that diabetes technology is feasible to implement in older adult populations and can reduce hypoglycemia without increasing hyperglycemia.
Conclusions:
Additional research testing these technologies among populations with age-related impairments is necessary, as are efforts to implement and ensure broad accessibility of these technologies across diverse care settings, including primary and geriatrics care.
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