Related Experiment Video
Updated: Sep 16, 2025

Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
Published on: September 2, 2025
Efficient needle guidance: multi-camera augmented reality navigation without patient-specific calibration
Yizhi Wei1,2, Bingyu Huang3,4, Bolin Zhao1
1School of Engineering, Huaqiao University, Quanzhou, 362021, China.
Purpose:
Augmented reality (AR) technology holds significant promise for enhancing surgical navigation in needle-based procedures such as biopsies and ablations. However, most existing AR systems rely on patient-specific markers, which disrupt clinical workflows and require time-consuming preoperative calibrations, thereby hindering operational efficiency and precision.
Methods:
We developed a novel multi-camera AR navigation system that eliminates the need for patient-specific markers by utilizing ceiling-mounted markers mapped to fixed medical imaging devices. A hierarchical optimization framework integrates both marker mapping and multi-camera calibration. Deep learning techniques are employed to enhance marker detection and registration accuracy. Additionally, a vision-based pose compensation method is implemented to mitigate errors caused by patient movement, improving overall positional accuracy.
Results:
Validation through phantom experiments and simulated clinical scenarios demonstrated an average puncture accuracy of 3.72 ± 1.21 mm. The system reduced needle placement time by 20 s compared to traditional marker-based methods. It also effectively corrected errors induced by patient movement, with a mean positional error of 0.38 pixels and an angular deviation of 0.51 . These results highlight the system's precision, adaptability, and reliability in realistic surgical conditions.
Conclusion:
This marker-free AR guidance system significantly streamlines surgical workflows while enhancing needle navigation accuracy. Its simplicity, cost-effectiveness, and adaptability make it an ideal solution for both high- and low-resource clinical environments, offering the potential for improved precision, reduced procedural time, and better patient outcomes.

