Hemodynamic response of elderly patients undergoing major surgery under moderate normovolemic hemodilution

Moderate normovolemic hemodilution (MNH) is used in general surgery not only when major blood loss is anticipated but also as a prophylactic measure for the prevention of postoperative deep vein thrombosis. The hemodynamic effects of MNH (hematocrit value 27-29%) with dextran 70 as diluent were evaluated in 50 patients undergoing major surgery (cholecystectomy or total hip arthroplasty). They were divided into two groups according to age: I less than 60; II greater than 60 years. Comparison of the results obtained in the two groups shows no significant difference between them, either before or after hemodilution. Our study shows that MNH is a safe procedure, not only in young patients but also in those over 60 years.