[Reliability of automatic blood coagulometer (KC-10) on some species of experimental animals]

Prothrombin time, activated partial thromboplastin time and fibrinogen determinations of some species of experimental animals with automatic coagulometer KC-10 were examined in regard to reliability and usefulness. In the examinations of within-run precision of the undiluted and diluted plasma of dog, rabbit and rat, the results were acceptable. In the examinations of capability detecting N-nitrosodimethylamine-induce coagulopathy of rats, the results were found to be accurate. The comparison studies between KC-10 and the reference instrument AUTO-FI indicated good correlations. These results supported the reliability and usefulness of use of automatic coagulometer for blood coagulability test on experimental animals.