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Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
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Patterns and Outcomes of Limb Amputations: A Single-Center Retrospective Study
Saad M Alqahtani1, Omar Bamalan2, Hussain Aljubran1
1Department of Orthopedic Surgery, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
The Journal of Surgical Research
|July 13, 2025
Summary
Limb amputations present significant challenges, with a notable rate of complications and revisions observed. Comprehensive postoperative care, including rehabilitation and emotional support, is crucial for patient well-being.
Area of Science:
- Medical research
- Clinical outcomes
- Patient quality of life
Background:
- Limb amputations remain a common procedure worldwide, despite medical advancements.
- The procedure significantly impacts patients' mental and physical health.
- Understanding amputation characteristics and quality of life is essential.
Purpose of the Study:
- To analyze clinical characteristics of limb amputations.
- To assess the quality of life in individuals undergoing amputation.
- To identify factors associated with complications and revisions.
Main Methods:
- Retrospective single-center study.
- Inclusion of 268 patients from 2015-2021.
- Collection of demographic, clinical data, and Short Form-36 outcomes.
Main Results:
- Lower extremity amputations for peripheral vascular disease had higher complication rates.
- 16.8% of cases experienced complications, and 12.3% required revisions.
- Patients reported better health change scores but lower role-limitation scores.
Conclusions:
- High rates of complications and revisions necessitate improved amputation care.
- A multimodal approach integrating surgical, rehabilitative, and emotional support is recommended.
- Comprehensive postoperative assessment is vital for optimizing patient outcomes.

