Related Experiment Video
Updated: Sep 15, 2025

07:34
FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
37.0K
Relational dynamite: Engagements with kinship at the interface of donor conception and DNA testing
Petra Nordqvist1, Leah Gilman2, Caroline Redhead2
1University of Manchester, Manchester, M13 9PL, UK.
Social Science & Medicine (1982)
|July 13, 2025
Summary
Direct-to-Consumer Genetic Testing (DTCGT) reveals genetic relatives, impacting donor-conceived individuals. Responses to DNA matches range from embrace to reject, influencing family dynamics and kinship understanding.
Area of Science:
- Sociology
- Genetics
- Family Studies
Background:
- Direct-to-Consumer Genetic Testing (DTCGT) is increasingly accessible.
- Donor conception creates individuals with unknown genetic relatives.
- Existing research lacks understanding of DTCGT's impact on donor-conceived populations.
Purpose of the Study:
- Investigate how DTCGT affects donor-conceived individuals.
- Analyze responses to DNA matches within this population.
- Explore the intersection of genetic information and established kinship.
Main Methods:
- Qualitative analysis of empirical data.
- Theoretical engagement with kinship and personal life debates.
- Conceptual framework development for understanding responses to genetic matches.
Main Results:
- Individuals respond to DNA matches on a spectrum from embrace to reject.
- Navigating 'born and bred' kinship and 'accelerated kinship' is crucial.
- Family kinship structures (ontology, belonging, relationality, emotionality, power, temporality) shape responses.
Conclusions:
- Responses to genetic matches are relational and context-dependent.
- DTCGT can act as 'relational dynamite,' significantly altering family dynamics.
- Understanding these complex interactions is vital for donor-conceived individuals and their families.
Related Concept Videos
Gene Conversion
10.0K
Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
10.0K
Behavioral Genetics and Its Designs
529
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
529
DNA as a Genetic Template
22.8K
Two structural features of the DNA molecule provide a basis for the mechanisms of heredity: the four nucleotide bases and its double-stranded nature. The Watson-Crick model of double-helical DNA structure, proposed in 1952, drew heavily upon the X-ray crystallography work of researchers Rosalind Franklin and Maurice Wilkins. Watson, Crick, and Wilkins jointly received the Nobel Prize in Physiology or Medicine for their work in 1962. Franklin was, controversially, excluded from the prize for...
22.8K
Genomic Imprinting and Inheritance
35.3K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
35.3K
Animal Mitochondrial Genetics
8.0K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
8.0K
Crossing Over
148.0K
Unlike mitosis, meiosis aims for genetic diversity in its creation of haploid gametes. Dividing germ cells first begin this process in prophase I, where each chromosome—replicated in S phase—is now composed of two sister chromatids (identical copies) joined centrally.
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
The homologous pairs of sister chromosomes—one from the maternal and one from the paternal genome—then begin to align alongside each other lengthwise, matching corresponding DNA positions in a process...
148.0K

