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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
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Endophthalmitis due to a retained intraocular metallic object
Alan R Spicer1, Mostafa M Meleis2, Harry W Buchanan3
1Department of Emergency and Hospital Medicine, Lehigh Valley Health Network, Allentown, PA, USA; USF Morsani College of Medicine, USA.
The American Journal of Emergency Medicine
|July 13, 2025
Summary
Prompt diagnosis of endophthalmitis after eye trauma is crucial. A comprehensive slit lamp exam is vital for detecting retained foreign bodies, enabling timely treatment and preventing vision loss.
Area of Science:
- Ophthalmology
- Emergency Medicine
- Infectious Diseases
Background:
- Endophthalmitis is a severe intraocular infection requiring urgent management.
- Diagnosis in the emergency department (ED) can be challenging due to nonspecific symptoms and specialized equipment needs.
Observation:
- A 42-year-old male presented with eye pain and blurred vision post-traumatic ocular injury.
- Initial fluorescein staining showed a corneal abrasion, treated with ointment.
- A subsequent ED visit revealed signs of endophthalmitis, with a retained metallic foreign body found in the anterior chamber via slit lamp examination.
Findings:
- The initial diagnosis of corneal abrasion was incomplete.
- A retained intraocular foreign body was the underlying cause of the endophthalmitis.
- Delayed diagnosis and treatment led to severe inflammation and vision compromise.
Implications:
- Emphasizes the critical role of a thorough slit lamp examination in all ocular trauma cases.
- Highlights the need for advanced diagnostic capabilities in the ED for ocular emergencies.
- Underscores the importance of prompt treatment with intravitreal antibiotics for endophthalmitis to preserve vision.
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