Minimally invasive surgery for giant splenic cysts

Patients diagnosed with solitary non-parasitic splenic cysts were mainly described in the literature as case reports or case series. This study aims to analyse data from published articles about this condition. We performed a systematic review using the PRISMA protocol. PubMed/MEDLINE, Embase and the Google Scholar Library were searched up to the end of May 2024. Fifty-five patients were included in this study. 31 (56.36%) patients are female, and the mean age is 29.13 years. 32 (58%) patients experienced abdominal pain and 5 (9%) patients were asymptomatic. Sizes of the cysts varied between 67 and 250 mm. Most of the patients underwent laparoscopic fenestration of the cyst (54.55%), and all the pathological results were benign lesions. 3 minor complications (5.45%) were observed and recurrence of the cyst occurred in 3 patients (5.45%). Solitary non-parasitic splenic cysts are uncommon. They are benign lesions but can become symptomatic and therefore require surgery. Minimally invasive surgery is a safe option with a very low morbidity and mortality.