Related Experiment Video
Updated: Sep 15, 2025

A Protocol for Real-time 3D Single Particle Tracking
Published on: January 3, 2018
A novel SGRT system for real-time optical surface tracking or guidance
Xinmin Liu1, Daniel Alexander2, Daniel Kayser3
1Department of Radiation Oncology, UCLA, Los Angeles, California, USA.
The LUNA 3D system offers precise optical 3D surface imaging for radiation therapy, achieving sub-millimeter accuracy and minimal sensitivity to lighting or surface color variations.
Area of Science:
- Medical Physics
- Optical Imaging
- Radiation Therapy Technology
Background:
- Optical 3D surface imaging reconstructs patient surfaces without markers.
- Surface-guided radiation therapy (SGRT) relies on accurate surface tracking.
Purpose of the Study:
- Evaluate the novel LUNA 3D system for SGRT.
- Assess static and dynamic accuracy under various conditions (color, lighting, ROI size).
Main Methods:
- Used a 6DoF robot stage with head phantoms for accuracy testing.
- Employed an infrared (IR) tracking camera for secondary verification.
- Utilized blue light projection and narrow bandpass filters to mitigate environmental variations.
Main Results:
- Achieved sub-millimeter translational (0.04-0.06 mm) and sub-degree rotational (0.04°) accuracy for static phantoms.
- Showed minimal difference (max 0.14 mm) compared to IR tracking across varying conditions.
- Maintained a consistent frame rate of 12.5 fps regardless of Region of Interest (ROI) size.
Conclusions:
- LUNA 3D provides high sub-millimeter/sub-degree tracking accuracy.
- Demonstrated robustness against surface color and ambient light changes.
- Offered stable frame rate performance irrespective of ROI size, suitable for SGRT.
More Related Videos
10:23Technical Approach for Infrared Tracking for Soft Tissue Navigation with a Holographic Head-Mounted Display and Preclinical Validation
Published on: September 2, 2025
11:283D Orbital Tracking in a Modified Two-photon Microscope: An Application to the Tracking of Intracellular Vesicles
Published on: October 1, 2014