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Related Concept Videos

Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...

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Procedural Outcomes and Conduction System Capture Pattern Maintenance With the Tendril STS™ 2088TC Lead and CPS

Ayodeji Dina1,2, Karina Demchuk1,2, Ioannis Koulouridis1,2

  • 1Department of Medicine, Division of Cardiology, Section of Electrophysiology, Boston Medical Center - Brighton, Boston, Massachusetts, USA.

Journal of Cardiovascular Electrophysiology
|July 14, 2025
PubMed
Summary

Stylet-driven leads (SDL) offer a viable alternative to lumenless leads for left bundle branch area pacing (LBBAP), showing similar acute performance. Long-term conduction system capture maintenance requires further investigation.

Keywords:
conduction system captureconduction system pacingleft bundle branch area pacingleft bundle branch blocklumenless leadphysiological pacingresynchronization therapystylet‐driven lead

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Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Device Technology

Background:

  • Left bundle branch area pacing (LBBAP) traditionally uses lumenless (LLL) Medtronic SelectSecure™ Model 3830 leads.
  • Stylet-driven leads (SDL) have recently been introduced for LBBAP procedures.

Purpose of the Study:

  • To compare the acute and chronic performance of the Abbott Tendril STS™ 2088TC SDL and CPS Locator™ 3D delivery system.
  • To evaluate the safety and efficacy of SDL compared to LLL in LBBAP.

Main Methods:

  • A prospective study of 50 patients receiving SDL via the CPS Locator™ 3D delivery system.
  • Comparison with a retrospective cohort of 229 LLL patients.
  • Evaluation of procedural outcomes, lead performance, and follow-up data.

Main Results:

  • LBBAP success rates were comparable between SDL (84%) and LLL (79%) groups.
  • No significant differences in procedural characteristics or complications were observed.
  • While acute conduction system capture (CSC) was similar, a significantly longer QRS duration at follow-up in the SDL group suggests potential long-term CSC loss.

Conclusions:

  • SDL represents a viable alternative to LLL for LBBAP, with comparable acute and midterm pacing parameters.
  • The CPS Locator™ 3D delivery system demonstrated comparable performance and safety.
  • Further studies are needed to assess the long-term maintenance of CSC with SDL.