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Wild Honey Intoxication: A Case Series From Nepal
Rukma Raj Kafle1, Rakshya Arun Kandel1, Sabin Chaulagain2
1Department of Emergency Medicine Scheer Memorial Adventist Hospital Banepa Nepal.
Clinical Case Reports
|July 14, 2025
Summary
Wild honey poisoning can lead to severe heart problems like slow heart rate and low blood pressure, even from small doses. Prompt treatment with fluids and atropine is usually effective, but severe cases may need vasopressors.
Area of Science:
- Toxicology
- Cardiology
- Emergency Medicine
Background:
- Wild honey can contain grayanotoxins, leading to a condition known as "mad honey poisoning."
- Cardiovascular complications are a significant concern in grayanotoxin ingestion.
Purpose of the Study:
- To summarize the cardiovascular effects of wild honey poisoning.
- To outline the typical onset and effective treatment strategies.
Main Methods:
- Review of clinical presentations and outcomes associated with wild honey ingestion.
- Analysis of treatment protocols for cardiovascular complications.
Main Results:
- Ingestion of small amounts (1-2 teaspoons) can cause bradycardia and hypotension.
- Symptoms usually appear within 30-45 minutes of consumption.
- Most cases respond well to intravenous fluids and atropine.
Conclusions:
- Wild honey poisoning presents with significant cardiovascular risks.
- Early and appropriate medical intervention is crucial for favorable outcomes.
- Delayed presentation may necessitate the use of vasopressors for severe hypotension.
