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Comparative Evaluation of Advanced Platelet-Rich Fibrin and Blood Clot as Scaffolds in Regenerative Endodontics for
Seema Qamar1, Arnab Mondal1, Swati Singh1
1Department of Pediatric and Preventive Dentistry, Hazaribag College of Dental Sciences and Hospital, Hazaribag, Jharkhand, India.
Background:
In immature necrotic teeth, the goal of regenerative endodontic treatments (REPs) is to promote root growth. This research compares the efficacy of traditional blood clots and advanced platelet-rich fibrin (A-PRF) as scaffolds for the regeneration of injured nonvital immature teeth.
Materials And Methods:
This randomized clinical experiment comprised 30 injured nonvital immature maxillary incisors from 24 kids between the ages of 8 and 12. The canals were irrigated with 1.5% sodium hypochlorite and 17% EDTA after minor mechanical debridement. For disinfection, calcium hydroxide paste was used. Two sets of teeth-A-PRF (n = 15) and conventional blood clot (n = 15)-were assigned at random. At baseline, three, six, and 12 months, radiographic measurements were made of the root development parameters, such as apical breadth, root length, and root thickness. To evaluate changes over time both within and across groups, statistical analyses were conducted.
Results:
The investigation was finished by 28 teeth (A-PRF: n = 14, blood clot: n = 14). After a year, teeth treated with A-PRF had a greater increase in root length (18.5% vs. 12.2%), root thickness (15.4% vs. 11.6%), and a decrease in apical width (11.3% vs. 8.1%) than the blood clot group. Nevertheless, there was no statistically significant difference between the two groups (P > 0.05). For the length of the trial, none of the patients in either group had any symptoms.
Conclusion:
A-PRF and traditional blood clot scaffolds both showed significant enhancements in REP root growth. A-PRF demonstrated marginally better results and is especially helpful when it comes to difficult bleeding induction or when there is a danger of close proximity to critical structures.
