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"Insights into HbA1c: Key Role in Diabetes Screening and Associated Conditions" - A Comprehensive Review

Meksha Mehta1, Arun Prasad2, Varaprasad Kalapureddy3

  • 1Final Year Medical Student, Symbiosis Medical College for Women, Symbiosis International (Deemed) University, Lavale, Pune, Maharashtra, India.

Journal of Pharmacy & Bioallied Sciences
|July 14, 2025
PubMed

Insights

Glycated hemoglobin (HbA1c) is crucial for monitoring long-term diabetes management, reflecting average glucose over 8-12 weeks. Accurate HbA1c interpretation guides effective diabetes therapy decisions.

Area of Science:

  • Endocrinology and Metabolism
  • Clinical Diagnostics

Background:

  • Diabetes Mellitus (DM) is a significant global health concern, leading to severe complications like stroke, blindness, renal failure, and amputation.
  • Effective management of DM relies on accurate monitoring of long-term glycemic control.

Purpose of the Study:

  • To highlight the importance of Glycated Hemoglobin (HbA1c) as a key biomarker in diabetes management.
  • To emphasize the necessity of precise HbA1c interpretation for optimizing patient therapy and outcomes.

Main Methods:

  • Review of current literature and guidelines on Glycated Hemoglobin (HbA1c) testing.
  • Analysis of HbA1c's role in reflecting average glucose levels over 8-12 weeks.

Main Results:

  • HbA1c is recognized by the World Health Organization (WHO) as the gold standard for monitoring diabetes.
  • Effective interpretation of HbA1c levels is essential for predicting and preventing diabetes-related complications.

Conclusions:

  • Glycated Hemoglobin (HbA1c) is indispensable for long-term glycemic management in diabetes.
  • Accurate HbA1c interpretation is critical for guiding effective therapeutic interventions and improving patient prognosis.

Keywords:
Blood glucoseHbA1cdiabeteslong-term glycemic index

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