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Prenatal affective cognitive training: A proof-of-concept study
Anne J Bjertrup1, Tue H Petersen2, Nynne Beier1
1Copenhagen Affective Disorders Research Center (CADIC), Psychiatric Centre Copenhagen, Mental Health Services, Denmark.
Neuroscience Applied
|July 14, 2025
Summary
A two-week affective cognitive training intervention improved pregnant individuals' cognitive responses to infant stimuli, showing increased sensitivity to happy faces and reduced distress reactivity. This may reduce postpartum depression risk.
Area of Science:
- Psychology
- Neuroscience
- Perinatal Mental Health
Background:
- Negative cognitive bias towards infant stimuli during pregnancy is a risk factor for postpartum depression (PPD).
- Targeting these cognitive biases may offer a novel preventative strategy for PPD.
Purpose of the Study:
- To assess the feasibility and effects of a brief affective cognitive training intervention.
- To investigate changes in cognitive responses to emotional infant stimuli in pregnant individuals at risk for PPD.
Main Methods:
- A proof-of-concept study involving 43 pregnant participants (23 high-risk, 20 low-risk for PPD).
- A two-week affective cognitive training intervention was administered.
- Cognitive responses to infant stimuli were measured at baseline, post-intervention, and follow-up.
Main Results:
- The intervention was feasible, with 80% completion and positive feedback.
- Participants showed increased sensitivity to happy infant faces, greater attention to infant stimuli, and reduced negative reactivity to infant distress.
- Improved sensitivity to happy infant faces correlated with fewer depressive symptoms six months postpartum.
Conclusions:
- Prenatal affective cognitive training is feasible and positively impacts cognitive responses to infant stimuli.
- Findings suggest potential for this intervention in reducing PPD risk, warranting further investigation.
- Larger randomized controlled trials are needed to confirm efficacy in preventing PPD.
Keywords:
AttachmentCognitive neuropsychiatryEmotional cognitionInfant developmentMother-infant interactionPregnancy
