Antibiotic Misuse: An In-Depth Examination of Its Global Consequences and Public Health Challenges

Jeevan Nammi1, Roshini Pasala1, Nikhil Andhe1

  • 1Medicine, Siddhartha Medical College, Vijayawada, IND.

Cureus
|July 14, 2025
PubMed

Insights

Antibiotic misuse fuels antimicrobial resistance (AMR), threatening global health. Addressing this requires collective action from healthcare workers, patients, and governments through education, policy, and better diagnostics to preserve antibiotic effectiveness.

Area of Science:

  • Microbiology
  • Public Health
  • Health Policy

Background:

  • Antibiotic misuse is a significant global challenge.
  • Antimicrobial resistance (AMR) is rising due to widespread antibiotic misuse.
  • AMR threatens effective treatment of infections and patient survival.

Purpose of the Study:

  • To examine the drivers and patterns of antibiotic misuse worldwide.
  • To explore the multifaceted consequences of AMR on individuals, healthcare systems, and economies.
  • To identify key stakeholders and discuss potential solutions to combat antibiotic misuse and AMR.

Main Methods:

  • Literature review and analysis of global antibiotic usage patterns.
  • Examination of contributing factors: overprescribing, self-medication, and regulatory gaps.
  • Case studies illustrating the impact of AMR on healthcare and economic systems.

Main Results:

  • Antibiotic misuse is prevalent globally, driven by diverse factors including clinical practices and patient behaviors.
  • Antimicrobial resistance poses severe risks, impacting treatment efficacy, healthcare costs, and economic stability.
  • Stakeholder roles (healthcare workers, patients, governments, industry) are critical in both exacerbating and mitigating the problem.

Conclusions:

  • Reversing antibiotic misuse is achievable through a multi-pronged approach.
  • Enhanced education, stringent policies, advanced diagnostics, and coordinated strategies are essential.
  • Global collaboration is imperative to preserve the efficacy of antibiotics for future generations.

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