Related Experiment Video
Updated: Sep 15, 2025

Steps for the Autologous Ex vivo Perfused Porcine Liver-kidney Experiment
Published on: December 18, 2013
Single-Pass Albumin Dialysis (SPAD) as a Therapeutic Extracorporeal Liver Support in a Low-Resource Setting: Case
David Roman Hernández1, Alicia Valdez-Gaona1, Luis Arturo García-Velasco1
1Intensive Care Unit, Hospital General "Dr. Manuel Gea Gonzalez", Mexico City, MEX.
Abstract:
Acute liver failure, a condition marked by high mortality, leads to a loss of liver function that impairs the detoxification of substances such as bilirubin, ammonia, and lactate, as well as the liver's synthetic functions, causing damage to other organs. New extracorporeal therapies, including single-pass albumin dialysis (SPAD), have been developed to support liver function. We present a case of a 25-year-old male with no significant past medical history who presented with multiple organ failure and acute kidney injury that required continuous renal replacement therapy (CRRT) with continuous venovenous hemodiafiltration (CVVHDF), necessitating SPAD for the treatment of the liver failure.
More Related Videos
Related Concept Videos
Dialysis
Hemodialysis I: Introduction
Acute Kidney Injury V: Interprofessional Care
Peritoneal Dialysis I: Introduction and Procedure
Hemodialysis II: Procedure and Complications
Hemodialysis III: Nursing Management

