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Complex Hepatic Abscess in a Child Following Esophageal Procedures: Clinical Insights and Management
Jack Hachem1, Anthoula Christodoulou2, William Hunt3
1Pediatric Gastroenterology, Baylor College of Medicine, San Antonio, USA.
Insights
A rare hepatic abscess occurred in a child after esophageal procedures for caustic ingestion. This highlights the risk of serious infections and the need for prophylactic antibiotics in pediatric patients undergoing interventions.
Area of Science:
- Pediatric Gastroenterology
- Infectious Diseases
- Surgical Complications
Background:
- Caustic ingestion in children can lead to esophageal strictures requiring repeated interventions like balloon dilation and stenting.
- Esophageal interventions, particularly multiple procedures, carry a risk of iatrogenic complications.
- Hepatic abscess is a rare but serious complication that can arise from bacterial translocation.
Observation:
- A five-year-old girl developed a hepatic abscess following multiple esophageal balloon dilations and stenting for caustic-induced strictures.
- Clinical presentation included abdominal pain, fever, and anorexia.
- Imaging confirmed a complex hepatic abscess, with cultures identifying oral bacteria (Eikenella corrodens, Prevotella oralis).
Findings:
- Bacterial translocation from oral flora to the liver is a likely mechanism for abscess formation after esophageal mucosal disruption.
- Initial antibiotic treatment (ceftriaxone and metronidazole) showed improvement, but fever recurred upon switching antibiotics.
- The patient recovered with a return to the original antibiotic regimen and continued treatment.
Implications:
- This case emphasizes the potential for severe infectious complications following esophageal interventions in pediatric patients.
- Prophylactic antibiotics should be considered for high-risk pediatric patients undergoing repeated esophageal procedures.
- Effective management requires both appropriate antibiotic therapy and source control for hepatic abscesses.
Abstract:
This case report describes a rare occurrence of a hepatic abscess in a five-year-old girl following esophageal interventions due to caustic ingestion. Persistent strictures led to multiple balloon dilations and serial esophageal stents, after which she developed abdominal pain, fever, and anorexia. Imaging revealed a complex hepatic abscess. Cultures identified Eikenella corrodens and Prevotella oralis, organisms typically found in the oral cavity, suggesting bacterial translocation due to mucosal disruption from the esophageal procedures. The patient initially received ceftriaxone and metronidazole, showing improvement, but experienced fever recurrence upon switching to ampicillin/sulbactam, necessitating a return to the original antibiotic regimen. The patient eventually recovered with continued treatment, highlighting the risk of serious infections following esophageal interventions in pediatric patients. This case underscores the importance of considering prophylactic antibiotics to prevent such complications, especially in high-risk pediatric patients undergoing repeated interventions. When infectious complications do occur, both antibiotic management and source control are necessary for definitive treatment. Further research is needed to establish guidelines for prophylactic measures in similar clinical scenarios.
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