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Primary Intracranial Adenoid Cystic Carcinoma: A Case Report
Pralisha Maharjan1, Gopi Aryal1, Reena Rana1
1Department of Laboratory Medicine and Pathology, Nepal Mediciti Hospital, Lalitpur, Nepal.
JNMA; Journal of the Nepal Medical Association
|July 14, 2025
Summary
Primary intracranial adenoid cystic carcinoma (ACC), a rare aggressive cancer, was diagnosed in a 61-year-old male. Surgical removal of the cerebellopontine angle mass confirmed this rare diagnosis.
Area of Science:
- Neuro-oncology
- Pathology
Background:
- Adenoid cystic carcinoma (ACC) is a rare malignant tumor originating from mucous glands.
- Primary intracranial ACC is exceptionally rare, posing diagnostic challenges.
Observation:
- A 61-year-old male presented with dysphagia, dysarthria, and generalized weakness.
- MRI revealed a residual right cerebellopontine angle (CPA) mass causing mass effect and obstructive hydrocephalus.
Findings:
- Surgical excision of the CPA mass was performed via a right retrosigmoid craniotomy.
- Histopathological examination confirmed the diagnosis of primary intracranial ACC.
Implications:
- This case highlights the importance of considering rare diagnoses in neuro-oncology.
- Further research into the management and outcomes of intracranial ACC is warranted.

