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Related Experiment Video

Updated: Sep 15, 2025

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
05:39

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

568

Long-level Intramedullary Spinal Cord Tumor: A Case Series.

Namrata Khadka1, Anil Suryabanshi2, Apurva Shrestha1

  • 1Department of Neurosurgery, National Neurosurgical Referral Center, National Academy of Medical Sciences Bir Hospital, Kathmandu, Nepal.

JNMA; Journal of the Nepal Medical Association
|July 14, 2025
PubMed
Summary

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Srrm2 haploinsufficiency drives SynGAP-γ reduction, Agap3 mis-splicing, and oligodendrocyte deficits in a genetic mouse model of schizophrenia.

Cell reports·2026
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Pangolin Distribution and Predicted Habitat Loss From the Nagmati Dam in Shivapuri Nagarjun National Park, Nepal.

Ecology and evolution·2026
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Spatially resolved translational dysregulation in <i>Grin2a</i>+/- mouse model of schizophrenia.

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A framework for addressing racial and related inequities in conservation.

Nature·2026
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Elevated synaptic PKA activity and abnormal striatal dopamine signaling in <i>Akap11</i> mutant mice, a genetic model of schizophrenia and bipolar disorder.

bioRxiv : the preprint server for biology·2025
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Elevated synaptic PKA activity and abnormal striatal dopamine signaling in Akap11 mutant mice, a genetic model of schizophrenia and bipolar disorder.

Nature communications·2025

Long-level intramedullary spinal cord tumors are rare but challenging. Aggressive surgical resection and advanced techniques are key to improving patient prognosis and neurological outcomes.

Area of Science:

  • Neurosurgery
  • Oncology
  • Radiology

Background:

  • Spinal cord tumors, while uncommon, present significant challenges including neurological disability and mortality.
  • Long-level intramedullary spinal cord tumors represent a particularly complex clinical scenario requiring specialized management.

Observation:

  • Contrast-enhanced Magnetic Resonance Imaging (MRI) is crucial for diagnosis and surgical planning.
  • Aggressive surgical resection is recommended to improve prognosis, necessitating careful preservation of neurological function.

Findings:

  • Three cases of long-level intramedullary tumors are presented.
  • Details on clinical presentations, radiological findings, and histopathological results are provided.

Implications:

Keywords:
ependymomaintraoperative neuromonitoringlong-level intramedullaryspinal cord tumor

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  • Tailored management strategies are significant for optimizing outcomes in these challenging cases.
  • Advancements in spinal surgery and intraoperative monitoring offer improved patient outcomes.