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Perioperative Anticoagulation and Risk Assessment: Building a Bridge Over a STREAM
Anil Harrison1, Sushil Rayamajhi2
1Department of Medicine, Midwestern University, Glendale, Arizona, USA.
Insights
Physicians can use the STREAM mnemonic to identify high-risk patients needing bridging therapy during perioperative anticoagulation, balancing bleeding and thrombosis risks.
Area of Science:
- Cardiology
- Hematology
- Anesthesiology
Background:
- Perioperative care necessitates balancing bleeding and thrombosis risks.
- Current anticoagulation guidelines, including CHA2DS2-VASC and HAS-BLED scores, aid risk assessment but decision-making for bridging therapy remains complex.
- Bridging therapy with heparin is often used but carries its own risks.
Purpose of the Study:
- To provide a simple, memorable tool for identifying patients who require bridging anticoagulation therapy during the perioperative period.
- To aid clinicians in making informed decisions regarding anticoagulation management in high-risk surgical patients.
Main Methods:
- Development of the STREAM mnemonic, which encapsulates key high-risk factors for bridging therapy.
- The mnemonic highlights specific clinical scenarios: recent stroke or transient ischemic attack, severe thrombophilia, rheumatic valvular disease, recent venous thromboembolism, atrial fibrillation with high CHA2DS2-VASC scores, and mechanical heart valves.
Main Results:
- The STREAM mnemonic offers a structured approach to perioperative anticoagulation management.
- It identifies specific high-risk conditions necessitating bridging therapy, thereby optimizing patient care.
- Facilitates a methodical decision-making process to minimize both bleeding and thrombotic events.
Conclusions:
- The STREAM mnemonic serves as a valuable tool for physicians managing perioperative anticoagulation.
- It simplifies the identification of patients requiring bridging therapy, enhancing clinical judgment and patient safety.
- Optimizes the balance between preventing thrombosis and minimizing bleeding complications in surgical patients.
Abstract:
Perioperative care requires a comprehensive assessment of the risks of bleeding and thrombosis. The 2022 CHEST Guidelines offer an empirical foundation for customized treatment using clinical judgment and risk assessment based on CHA2DS2-VASC and HAS-BLED scores. Despite the ease of access to anticoagulation guidelines, decision-making remains challenging, particularly when determining the necessity of bridging therapy with unfractionated or low-molecular-weight heparin. To facilitate this decision, we provide a mnemonic, STREAM, that highlights high-risk situations that require bridging. These include recent stroke or transient ischemic attack, severe thrombophilia, rheumatic valvular disease, recent venous thromboembolism, atrial fibrillation with high CHA2DS2-VASC scores, and mechanical heart valves. This mnemonic offers physicians a methodical approach to optimize perioperative anticoagulation control while minimizing the risk of hemorrhage and thrombosis.
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