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Incidental Neoplasm and Histopathological Spectrum of Suspected Acute Appendicitis in Appendectomy Specimen: An
Archana Tiwari1, Pratima Sapkota1, Dipesh Shrestha1
1Department of Pathology, Lumbini Medical College, Palpa, Tansen, Nepal.
Introduction:
Acute appendicitis is the most common surgical emergency and histopathological studies are the gold standard for confirmation of clinical diagnosis and key methods of discovering appendiceal neoplasm. Appendiceal neoplasms are uncommon and are mostly identified by pathologic examination after appendectomy for presumed appendicitis as an incidental finding.
Methods:
An observational cross-section study was conducted at a Medical College from 1st August 2022 to 31st July 2024. Appendectomy specimens were included in the study after obtaining consent. Ethical approval was taken from the Institutional Review Committee (Reference number: IRC-LMC 05/S-22). Descriptive analysis was done, frequency and proportion were calculated.
Results:
Among 350 appendectomy cases, 30 (8.57%) cases had negative appendectomies. Out of total 320 patients, 183 (57.19%) were male and 137 (42.81%) were female. Histopathological findings suggestive of acute appendicitis were observed in 164 (51.25%) specimens and there were 6 (1.87%) specimens suggestive of neoplasms. Amongst the neoplasm of appendix 3 (0.94%) were carcinoid tumours.
Conclusions:
Appendiceal neoplasms are uncommon which was comparable to previous studies. Carcinoid tumour was the most common incidental neoplasm.
Insights
Histopathological examination of appendectomy specimens revealed that appendiceal neoplasms are uncommon, with carcinoid tumors being the most frequent incidental finding. This study highlights the importance of pathology in diagnosing these rare conditions.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Acute appendicitis is a common surgical emergency.
- Histopathological examination of appendectomy specimens is crucial for diagnosis and identifying appendiceal neoplasms.
- Appendiceal neoplasms are rare and often found incidentally during appendectomy for suspected appendicitis.
Purpose of the Study:
- To determine the incidence of appendiceal neoplasms.
- To identify the types of appendiceal neoplasms found.
- To analyze histopathological findings in appendectomy specimens.
Main Methods:
- An observational cross-sectional study was conducted.
- Appendectomy specimens from August 2022 to July 2024 were analyzed.
- Descriptive analysis, including frequency and proportion calculations, was performed.
Main Results:
- Out of 350 appendectomy cases, 30 (8.57%) were negative for appendicitis.
- Histopathological findings showed acute appendicitis in 164 (51.25%) specimens.
- Six (1.87%) specimens were suggestive of neoplasms, with 3 (0.94%) being carcinoid tumors.
Conclusions:
- Appendiceal neoplasms are uncommon, consistent with previous research.
- Carcinoid tumors were the most frequent type of incidental appendiceal neoplasm identified.
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