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MXene-Integrated Composites for Biomedical Applications: Synthesis, Cancer Diagnosis, and Emerging Frontiers
Aryan Saxena1, Akshayat Tyagi1, Sushipra Vats2
1Department of Applied Chemistry Delhi Technological University Delhi 110042 India.
Small Science
|July 14, 2025
Summary
MXenes, novel 2D nanomaterials, show promise in biomedicine, especially for cancer therapy. Research focuses on advanced synthesis and overcoming challenges for clinical use.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- MXenes are 2D transition metal carbides, carbonitrides, and nitrides with unique properties.
- Traditional MAX phase synthesis has limitations, driving interest in alternative non-MAX routes.
- MXenes offer potential in regenerative medicine, biosensing, and cancer therapy.
Purpose of the Study:
- To review advancements in MXene synthesis, focusing on non-MAX phase fabrication.
- To explore the biomedical applications of MXene-based composites.
- To discuss the potential of MXenes in cancer treatment, particularly photothermal and photodynamic therapy.
Main Methods:
- Review of existing literature on MXene synthesis and applications.
- Emphasis on non-MAX phase fabrication techniques.
- Analysis of MXene-based composites for cancer therapy.
Main Results:
- MXene-based composites demonstrate significant potential in cancer treatment.
- Photothermal and photodynamic therapies show particular promise with MXenes.
- Challenges in stability, drug release, and biodegradability are identified.
Conclusions:
- Advancements in MXene synthesis, especially non-MAX routes, are crucial.
- MXene composites offer novel strategies for cancer therapy.
- Further research is needed to address challenges for clinical translation.
