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Related Experiment Video

Updated: Sep 15, 2025

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
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Risk Factors for Candidozyma auris Among Admitted Patients in Riyadh, Saudi Arabia (2020-2022).

Fatimah S Alshahrani1,2,3, Abba Amsami Elgujja3, Sarah Alsubaie1,4

  • 1College of Medicine, King Saud University, Riyadh, 11362, Saudi Arabia.

Infection and Drug Resistance
|July 14, 2025
PubMed
Summary

This study identified key risk factors for Candida auris (C. auris) infection in a Saudi Arabian hospital. Comorbidities, prior hospital admissions, and high-risk unit stays were significant factors contributing to C. auris colonization or infection.

Keywords:
C. aurisCandidaCandida aurisMDROcandidaemiaemerging pathogensmultidrug-resistant organismsresistant pathogens

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Area of Science:

  • Infectious Diseases
  • Clinical Microbiology
  • Epidemiology

Background:

  • Candida auris (C. auris) is an emerging multidrug-resistant fungal pathogen causing invasive infections.
  • C. auris poses a significant threat in healthcare settings due to its persistence and high mortality rates.
  • Critically ill and immunocompromised patients are particularly vulnerable to C. auris infections.

Purpose of the Study:

  • To identify and analyze the risk factors associated with Candida auris (C. auris) infection and colonization in hospitalized patients.
  • To understand the epidemiological profile of C. auris cases in Riyadh, Saudi Arabia.

Main Methods:

  • A descriptive cross-sectional study was conducted involving 53 patients with C. auris identified between 2020 and 2022.
  • Retrospective review of patient records to determine risk factors.
  • Utilized a risk assessment tool for patient triage upon admission.

Main Results:

  • Comorbidities (85%), previous hospital admissions (50.9%), and admission to high-risk units (35%) were the primary identified risk factors.
  • Other contributing factors included the presence of wounds (34%), medical devices (32.1%), and prior antimicrobial use (22%).
  • The study included 53 patients (20 female, 33 male) aged 15-98 years.

Conclusions:

  • The identified risk factors for C. auris infection/colonization align with findings from other international studies.
  • Understanding these risk factors is crucial for developing targeted prevention and control strategies in hospital settings.
  • Further research may elucidate specific mechanisms and refine clinical management protocols.