Chondromyxoid Fibroma of Phalanges

Chondromyxoid fibroma (CMF) is a rare, benign metaphyseal bone tumour characterised by a combination of chondroid, myxoid, and fibrous elements. It can affect any bone at any age, with no gender predilection. We report a case of CMF in a 47-year-old female patient who presented with swelling of the left little finger at a tertiary care hospital in Kolkata, India, in 2024. Imaging revealed a lobulated lesion originating from the middle phalanx of the left little finger, extending to involve the base of the distal phalanx. Fine needle aspiration cytology indicated a moderately cellular myxoid lesion. Histopathology, which remains crucial for diagnosis, showed a lobulated tumour with zones of spindle to stellate cells, associated with an abundant myxoid and chondroid matrix in the intercellular spaces. Treatment involves complete local excision with tumour-free margins, as recurrence may occur with local curettage.