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Updated: Sep 15, 2025

A Workflow for Lipid Nanoparticle LNP Formulation Optimization using Designed Mixture-Process Experiments and Self-Validated Ensemble Models SVEM
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Machine learning enabled multiscale model for nanoparticle margination and physiology based pharmacokinetics

Sahil Kulkarni1, Benjamin Lin2,3, Ravi Radhakrishnan1,3

  • 1University of Pennsylvania, Chemical and Biomolecular Engineering, Philadelphia, 19104, PA, USA.

Computers & Chemical Engineering
|July 14, 2025
PubMed

Keywords:
DeepONetFokker–PlanckHematocritMarginationNanoparticlesPBPK

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