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Primary Orbital Teratoma With Congenital Anophthalmia in a Neonate: A Rare Case With Histopathological and
Dejan M Rašić1,2, Dolika D Vasović1, Miroslav Knežević1,2
1Eye Hospital, University Clinical Centre of Serbia, Belgrade, Serbia.
Abstract:
This case report describes a rare instance of primary orbital teratoma with anophthalmia in a neonate. A 6-day-old female presented with a congenital right orbital swelling and absence of visible ocular structures. MRI revealed a large, well-vascularized orbital mass without intracranial extension, accompanied by malformations in the right cerebral hemisphere. Histopathological examination confirmed a benign, mature/mixed teratoma comprising elements from all three germ layers, including neuroectoderm, mesoderm, and endoderm, with no evidence of malignancy. The patient underwent successful orbital exenteration with an implant at 3 weeks of age.

