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Genome-Wide Meta-Analysis Identifies Five Single-Nucleotide Polymorphisms Associated With Both Vitiligo and Freckles

Jiayi Lu1,2, Yirui Wang1,2, Zhuo Li1,2

  • 1Department of Dermatology, The First Affiliated Hospital of Anhui Medical University, Hefei, China.

Journal of Cosmetic Dermatology
|July 14, 2025
PubMed
Summary

Genetic analysis reveals shared susceptibility factors between vitiligo and freckles, two common skin pigmentation disorders. Five single-nucleotide polymorphisms (SNPs) were identified, offering insights into their genetic basis and potential immune system links.

Keywords:
GWASMHCfrecklesmeta‐analysisvitiligo

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