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Updated: May 6, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
Epidemiologic validation of the National Healthcare Safety Network's updated Clostridioides difficile test method
Nicholas A Turner1,2,3, Barry Shelton3, Becky A Smith1,2,3
1Duke University Medical Center, Division of Infectious Diseases, Durham, NC, USA.
None:
This longitudinal survey examined the effect of the National Healthcare Safety Network's (NHSN) recently updated Clostridioides difficile test method definition on reporting of hospital-onset C. difficile. Among six hospitals with ≥ 5 years of data available, the updated NHSN definition was associated with improved concordance between predicted versus reported cases.
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