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Updated: Sep 15, 2025
05:25
Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
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Lower Urinary Tract Symptoms in Men: A Review
John T Wei1, Casey A Dauw1, Casey N Brodsky1
1Department of Urology, University of Michigan, Ann Arbor.
JAMA
|July 14, 2025
Summary
Lower urinary tract symptoms (LUTS) affect many older men, often due to benign prostatic hyperplasia (BPH). Treatments range from behavioral changes and medications to surgery, improving quality of life.
Area of Science:
- Urology
- Men's Health
- Geriatrics
Background:
- Lower urinary tract symptoms (LUTS) affect up to 40% of men over 50.
- Symptoms include urinary urgency, nocturia, and weak stream, impacting quality of life.
- LUTS can lead to serious complications like urinary retention and kidney insufficiency.
Purpose of the Study:
- To review the causes and treatments for LUTS in men.
- To discuss the efficacy of various therapeutic approaches.
Main Methods:
- Review of current literature on LUTS management.
- Analysis of behavioral therapies, pharmacologic agents, and surgical interventions.
Main Results:
- Behavioral therapies (pelvic floor PT, timed voiding) offer symptomatic improvement.
- Medications like alpha-blockers, 5-ARIs, and PDE5 inhibitors improve LUTS, with combination therapy being more effective.
- Surgical options, including TURP and minimally invasive procedures, are effective for refractory cases, with varying complication rates.
Conclusions:
- LUTS are common in aging men, primarily caused by BPH or overactive bladder.
- First-line treatments include behavioral and pharmacologic therapies.
- Surgical interventions provide effective solutions for complex or persistent symptoms.
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