Renal involvement by histiocytic medullary reticulosis

The case of a young man who died seven months after the diagnosis of histiocytic medullary reticulosis is reported. Autopsy and laboratory findings were consistent with a diagnosis of uremia. Liver, lymph nodes, spleen, and bone marrow were involved by neoplastic cells. In addition, the kidneys were massively involved by tumor. Previously published autopsy studies of this rare condition failed to demonstrate massive renal involvement.