Related Experiment Video
Updated: Sep 15, 2025

Olfactory Assays for Mouse Models of Neurodegenerative Disease
Published on: August 25, 2014
Trained dogs can detect the odor of Parkinson's disease
Nicola Rooney1,2, Drupad K Trivedi3, Eleanor Sinclair3
1Medical Detection Dogs, Milton Keynes, UK.
Abstract:
A definitive diagnostic test for Parkinson's disease (PD) remains elusive, so identification of potential biomarkers can facilitate diagnosis and early intervention. Two dogs were trained to distinguish between dry skin swabs obtained from people with Parkinson's (PwP) and control participants. After 38-53 weeks of training on 205 samples, the dogs were tested in a double-blind trial using 60 control and 40 target (drug-naïve PwP) samples. They each showed high sensitivity (70% and 80%) and specificity (90% and 98%). This supports previous findings that dogs can be trained to reliably detect the odor of PD.
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease: Overview
Neural Regulation
Olfaction
The olfactory receptors are embedded in the cilia of the...

