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Scanning Light Scattering Profiler SLPS Based Methodology to Quantitatively Evaluate Forward and Backward Light Scattering from Intraocular Lenses

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Published on: June 6, 2017

Exudative AMD Risk Following Blue Light-Filtering IOL Implantation: A Population-Based Study According to

Jin Yeong Kim¹, Sunyeup Kim², Jin Cho¹

¹From the Department of Ophthalmology (J.Y.K., J.C., J.S.L, C.S.L., S.H.B., S.S.K., Y.J.K), Institute of Vision Research, College of Medicine, Yonsei University, Severance Hospital, Seoul, Republic of Korea.

American Journal of Ophthalmology

|July 14, 2025

Summary

Blue light-filtering (BLF) intraocular lenses (IOLs) implanted during cataract surgery do not lower the risk of developing exudative age-related macular degeneration (AMD). This finding applies to the South Korean population, even for those with prior nonexudative AMD.

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Published on: May 26, 2023

Area of Science:

Ophthalmology
Public Health
Medical Technology

Background:

Age-related macular degeneration (AMD) is a leading cause of vision loss.
Intraocular lenses (IOLs) are implanted during cataract surgery.
Blue light-filtering (BLF) IOLs are designed to reduce blue light exposure, potentially offering protective benefits.

Purpose of the Study:

To investigate the association between blue light-filtering (BLF) intraocular lenses (IOLs) and the risk of developing exudative age-related macular degeneration (AMD).

Main Methods:

A nationwide, population-based cohort study utilized data from the Korean National Health Insurance Sharing Service (NHISS).
Individuals receiving BLF IOLs or clear IOLs in both eyes after cataract surgery between 2012 and 2018 were analyzed.
Kaplan-Meier analysis and Cox/Fine-Gray models assessed the 10-year cumulative incidence and hazard ratios for exudative AMD, adjusting for covariates.

Main Results:

The study compared 21,741 individuals with BLF IOLs to 56,357 with clear IOLs.
No significant difference in the 10-year cumulative incidence of exudative AMD was observed between the BLF IOL and clear IOL groups (1.8% vs. 1.7%).
Adjusted hazard ratios did not indicate a protective effect of BLF IOLs against exudative AMD in any subgroup.

Conclusions:

Blue light-filtering (BLF) intraocular lens (IOL) implantation following cataract surgery does not appear to reduce the risk of developing exudative age-related macular degeneration (AMD).
This conclusion holds true for the South Korean population and is consistent even in individuals with a history of nonexudative AMD.