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Related Experiment Video

Updated: Sep 15, 2025

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Patterns of Co-Occurring Pressure Injuries: A Data-Driven Study Using Real-World Clinical Records.

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Co-occurring pressure injuries (PrIs) affect nearly a quarter of patients and are linked to severe injuries. Risk factors include severe PrIs, Black or African American race, and spinal cord injury, necessitating targeted prevention strategies.

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Area of Science:

  • Clinical Informatics
  • Wound Care
  • Epidemiology

Background:

  • Pressure injuries (PrIs) are a significant healthcare concern.
  • Understanding the patterns and risk factors of co-occurring PrIs is crucial for effective patient management.
  • Real-world clinical data offers valuable insights into PrI prevalence and associated conditions.

Purpose of the Study:

  • To investigate the prevalence, patterns, and risk factors of co-occurring pressure injuries (PrIs) in a large healthcare system.
  • To develop and validate an electronic health record (EHR)-based phenotype for identifying patients with co-occurring PrIs.
  • To identify specific patient characteristics and injury types associated with the presence of multiple PrIs.

Main Methods:

  • Retrospective cohort study analyzing EHR data from adult patients with PrIs between 2015 and 2023.
  • Development and validation of an EHR-based phenotype to accurately identify co-occurring PrIs.
  • Utilized univariate analyses and binary logistic regression to determine risk factors for co-occurring PrIs.

Main Results:

  • Out of 18,195 patients with PrIs, 4,415 (24.3%) had co-occurring PrIs.
  • The validated EHR phenotype demonstrated high accuracy (0.96).
  • Severe PrIs (OR 3.47), Black or African American race (OR 1.45), and spinal cord injury (OR 1.32) were significantly associated with co-occurring PrIs.

Conclusions:

  • Co-occurring PrIs are common and strongly associated with increased injury severity.
  • A direct relationship exists between the number of PrIs and the severity of the injuries.
  • Findings highlight the need for targeted risk assessment and prevention strategies for co-occurring PrIs.