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Updated: Jun 20, 2026

Cellular Encapsulation in 3D Hydrogels for Tissue Engineering

Cellular Encapsulation in 3D Hydrogels for Tissue Engineering

Published on: October 26, 2009

Programmable metal ion-induced patterned multicolour carboxymethylcellulose-based fluorescent hydrogels for

Qiuyan Luo¹, Jia Jiang¹, Juguo Dai¹

¹College of Materials, Fujian Provincial Key Laboratory of Fire Retardant Materials, Xiamen Key Laboratory of Fire Retardant Materials, Xiamen University, Xiamen 361005, China.

International Journal of Biological Macromolecules

|July 14, 2025

Summary

This study presents a novel fluorescent hydrogel for secure information encryption. The material changes color with metal ions, enabling programmable data storage and smartphone-readable encryption.

Keywords:

Carboxymethyl cellulose Multicolor fluorescent hydrogels Three-dimensional information encryption platform

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Light-mediated Formation and Patterning of Hydrogels for Cell Culture Applications

Light-mediated Formation and Patterning of Hydrogels for Cell Culture Applications

Published on: September 29, 2016

Area of Science:

Materials Science
Polymer Chemistry
Nanotechnology

Background:

Developing advanced materials for information encryption is crucial for data security.
Existing encryption methods face challenges in usability, security, and data capacity.

Purpose of the Study:

To create a novel interpenetrating polymer network hydrogel for enhanced information encryption.
To develop a multi-color fluorescent material responsive to specific stimuli for data encoding.

Main Methods:

Copolymerization of carboxymethyl cellulose and acrylamide to form an interpenetrating polymer network.
Incorporation of gold nanoclusters and coumarin derivatives for tunable fluorescence (red, blue, green).
Utilizing metal ion (Hg ²⁺ , Fe ³⁺ ) induced fluorescence changes for patterning and immobilization on various surfaces.

Main Results:

Successfully synthesized three types of fluorescent hydrogels with distinct emission colors.
Demonstrated responsive fluorescence changes to Hg ²⁺ and Fe ³⁺ ions, enabling precise patterning.
Achieved information encoding and encryption via physical/chemical stimuli, UV light, and smartphone scanning.

Conclusions:

The developed carboxymethyl cellulose-based fluorescent hydrogel offers a novel platform for advanced information storage.
The metal ion-induced, multi-color patterning strategy integrated with smartphone scanning meets demands for digital encryption.
The fluorescence quenching mechanism was elucidated, linked to specific functional groups within the hydrogel matrix.